Is the mattress protector hypoallergenic? April 20, 2022 13:43 Updated Yes, the mattress protector is made of cotton terry, which is designed to be both easy care and hypo-allergenic. Related articles Will the mattress protector reduce breathability of the mattress? How high are your foundations? How much storage is under the foundation? Is the mattress protector a full encasement? How long does it take to receive my refund? Do you use any chemical fire retardants (FR) in your mattresses?